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Walgreens
Walgreens was founded in 1901 in Chicago by Charles R. Walgreen Sr., who purchased the drugstore where he had previously worked as a pharmacist, and the company grew over the following century into one of the largest pharmacy chains in American history. The company is widely credited with popularizing the malted milkshake in the 1920s at its in-store soda fountains, a feature that became a defining part of the classic American drugstore experience for decades before being phased out of most locations. Walgreens merged with European pharmacy and health retail giant Alliance Boots in 2014 to form Walgreens Boots Alliance, creating one of the largest pharmacy-led health and wellness companies in the world with a footprint spanning multiple continents. Walgreens's combination of its century-plus American drugstore heritage, including its role popularizing the soda-fountain milkshake, and its transformative merger with Alliance Boots has made it one of the most globally significant pharmacy chains in the industry.
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Walmart Pharmacy
Walmart began adding in-store pharmacy counters to its supercenters starting in the 1970s and 1980s as part of the company's broader strategy of consolidating a wide range of everyday shopping needs, including groceries and prescriptions, under one roof. Walmart Pharmacy grew to become one of the largest pharmacy operations in the country by prescription volume, leveraging Walmart's massive existing store footprint across thousands of supercenter locations nationwide rather than building freestanding drugstore locations like its dedicated pharmacy-chain competitors. The company became particularly well known for its long-running $4 generic prescription drug program, introduced in 2006, which pressured competitors nationwide to offer similarly discounted generic drug pricing and reshaped consumer expectations around prescription costs. Walmart Pharmacy's combination of its integration into the country's largest retail footprint and its influential $4 generic drug pricing program has made it one of the most consequential forces in American prescription drug retail.
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